Low B6 intake linked to colorectal cancer study
An article published on the Nutraingredients website reveals scientific evidence into the link between low levels of vitamin B6 and colorectal cancer in men.
The article stated the following:
The study, published in this month's Journal of Nutrition, evaluated the intake of range of B-vitamins among 81,184 subjects taking part in the Japan Public Health Center-based Prospective Study.
The results also appeared to show that men with higher alcohol intake also benefited from the potentially protective effects of vitamin B6.
"Our results support previous evidence that low vitamin B-6 intake is associated with an increased risk of colorectal cancer. In particular, a higher intake of vitamin B-6 appears beneficial in men with higher alcohol intake," wrote lead author Junko Ishihara from Japan's National Cancer Center in collaboration with researchers from Gunma University Graduate School of Medicine.
Ishihara and co-workers used a 138-item self-administered food frequency questionnaire (FFQ) to quantify the intakes of folate, vitamin B-6, vitamin B-12, and methionine among 38,107 men and 43,077 women. The participants were followed from 1995-1998.
By the end of 2002, 526 cases of colorectal cancer (335 men, 191 women) had been diagnosed amongst the cohort.
Only increased vitamin B6 intake was found to impart a statistically significant benefit on male participants, with the highest intakes associated with a 31 per cent reduction in colorectal cancer risk, compared to the lowest intakes.
For the full article see link at end of email.
Vitamin B6 (Pyridoxine)
Vitamin B6 is a water-soluble vitamin that exists in three major chemical forms: pyridoxine, pyridoxal, and pyridoxamine. It performs a wide variety of functions in your body and is essential for your good health. For example, vitamin B6 is needed for more than 100 enzymes involved in protein metabolism. It is also essential for red blood cell metabolism. The nervous and immune systems need vitamin B6 to function efficiently, and it is also needed for the conversion of tryptophan (an amino acid) to niacin (a vitamin).
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